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Chloroquine against malaria, cancers and viral diseases
Quinoline (QN) derivatives are often used for the prophylaxis and treatment of malaria. Chloroquine (CQ), a protonated, weakly basic drug, exerts its antimalarial effect mainly by increasing pH and accumulating in the food vacuole of the parasites. Repurposing CQ is an emerging strategy for new indi...
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| Veröffentlicht in: | Drug Discov Today |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Ltd.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7492153/ https://ncbi.nlm.nih.gov/pubmed/32947043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.09.010 |
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