Chloroquine against malaria, cancers and viral diseases

Quinoline (QN) derivatives are often used for the prophylaxis and treatment of malaria. Chloroquine (CQ), a protonated, weakly basic drug, exerts its antimalarial effect mainly by increasing pH and accumulating in the food vacuole of the parasites. Repurposing CQ is an emerging strategy for new indi...

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Podrobná bibliografie
Vydáno v:Drug Discov Today
Hlavní autoři: Zhou, Wenmin, Wang, Hui, Yang, Yuqi, Chen, Zhe-Sheng, Zou, Chang, Zhang, Jianye
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492153/
https://ncbi.nlm.nih.gov/pubmed/32947043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.09.010
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