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Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
The Polycomb repressive complex 2 (PRC2) is a multicomponent histone H3K27 methyltransferase complex, best known for silencing the Hox genes during embryonic development. The Polycomb-like proteins PHF1, MTF2, and PHF19 are critical components of PRC2 by stimulating its catalytic activity in embryon...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7492083/ https://ncbi.nlm.nih.gov/pubmed/32869745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58675 |
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