Selection of Macrolide and Non-Macrolide Resistance with Mass Azithromycin Distribution: A Community-Randomized Trial

BACKGROUND: Biannual mass azithromycin distributions to preschool children for 2 years have been shown to reduce childhood mortality in sub-Saharan Africa, but at the cost of amplifying macrolide resistance. Here we investigated the gut resistome of children after 4 additional biannual distributions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:N Engl J Med
Prif Awduron: Doan, Thuy, Worden, Lee, Hinterwirth, Armin, Arzika, Ahmed M., Maliki, Ramatou, Abdou, Amza, Zhong, Lina, Chen, Cindi, Cook, Catherine, Lebas, Elodie, O’Brien, Kieran S., Oldenburg, Catherine E., Chow, Eric D., Porco, Travis C., Lipsitch, Marc, Keenan, Jeremy D., Lietman, Thomas M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Massachusetts Medical Society 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492079/
https://ncbi.nlm.nih.gov/pubmed/33176084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2002606
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