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The Intricate Coupling Between STIM Proteins and Orai Channels

Store-operated Ca(2+) entry signals are critical for cellular regulation. This intricate signaling pathway involves coupling of proteins in two different membranes: the ER-resident Ca(2+)-sensing STIM proteins and the highly Ca(2+)-selective PM Orai channels. The molecular nature of the STIM-Orai co...

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Bibliographic Details
Published in:Curr Opin Physiol
Main Authors: Baraniak, James H., Zhou, Yandong, Nwokonko, Robert M., Gill, Donald L.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491751/
https://ncbi.nlm.nih.gov/pubmed/32954113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cophys.2020.07.018
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