Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking: Development and Validation in Samples Collected from Adolescents and Adults

BACKGROUND: Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biom...

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Pubblicato in:Environ Health Perspect
Autori principali: Rauschert, Sebastian, Melton, Phillip E., Heiskala, Anni, Karhunen, Ville, Burdge, Graham, Craig, Jeffrey M., Godfrey, Keith M., Lillycrop, Karen, Mori, Trevor A., Beilin, Lawrence J., Oddy, Wendy H., Pennell, Craig, Järvelin, Marjo-Riitta, Sebert, Sylvain, Huang, Rae-Chi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Environmental Health Perspectives 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491641/
https://ncbi.nlm.nih.gov/pubmed/32930613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP6076
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