Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease

CONTEXT: “Accelerated aging,” assessed by adult DNA methylation, predicts cardiovascular disease (CVD). Adolescent accelerated aging might predict CVD earlier. We investigated whether epigenetic age acceleration (assessed age, 17 years) was associated with adiposity/CVD risk measured (ages 17, 20, a...

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Dades bibliogràfiques
Publicat a:J Clin Endocrinol Metab
Autors principals: Huang, Rae-Chi, Lillycrop, Karen A, Beilin, Lawrence J, Godfrey, Keith M, Anderson, Denise, Mori, Trevor A, Rauschert, Sebastian, Craig, Jeffrey M, Oddy, Wendy H, Ayonrinde, Oyekoya T, Pennell, Craig E, Holbrook, Joanna D, Melton, Phillip E
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Clinical Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555851/
https://ncbi.nlm.nih.gov/pubmed/30785999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02076
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