Maternal Smoking During Pregnancy Induces Persistent Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

Background: Several studies have shown effects of current and maternal smoking during pregnancy on DNA methylation of CpG sites in newborns and later in life. Here, we hypothesized that there are long-term and persistent epigenetic effects following maternal smoking during pregnancy on adolescent of...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Rauschert, Sebastian, Melton, Phillip E., Burdge, Graham, Craig, Jeffrey M., Godfrey, Keith M., Holbrook, Joanna D., Lillycrop, Karen, Mori, Trevor A., Beilin, Lawrence J., Oddy, Wendy H., Pennell, Craig, Huang, Rae-Chi
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Genetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764289/
https://ncbi.nlm.nih.gov/pubmed/31616461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00770
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