Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

SARS-CoV-2 spike (S) mediates entry into cells and is critical for vaccine development against COVID-19. S is synthesized as a precursor, processed into S1 and S2 by furin proteases, and activated for fusion when human angiotensin-converting enzyme 2 (hACE2) engages the receptor-binding domain (RBD)...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :bioRxiv
Главные авторы: Lu, Maolin, Uchil, Pradeep D., Li, Wenwei, Zheng, Desheng, Terry, Daniel S, Gorman, Jason, Shi, Wei, Zhang, Baoshan, Zhou, Tongqing, Ding, Shilei, Gasser, Romain, Prevost, Jeremie, Beaudoin-Bussieres, Guillaume, Anand, Sai Priya, Laumaea, Annemarie, Grover, Jonathan R., Lihong, Liu, Ho, David D, Mascola, John, Finzi, Andres, Kwong, Peter D., Blanchard, Scott C., Mothes, Walther
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491513/
https://ncbi.nlm.nih.gov/pubmed/32935100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.10.286948
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы