Sub-Nanometer Structures of HIV-1 Envelope Trimers on Aldrithiol-2 Inactivated Virus Particles

The HIV-1 envelope glycoprotein (Env) trimer, comprised of gp120 and gp41 subunits, mediates entry into cells. Recombinant Env trimers have been studied structurally, but characterization of Env embedded in intact virus membranes has been limited to low resolution. Here, we deploy cryo-electron tomo...

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Publicado en:Nat Struct Mol Biol
Main Authors: Li, Ze, Li, Wenwei, Lu, Maolin, Bess, Julian, Chao, Cara W., Gorman, Jay, Terry, Daniel S., Zhang, Baoshan, Zhou, Tongqing, Blanchard, Scott C., Kwong, Peter D., Lifson, Jeffrey D., Mothes, Walther, Liu, Jun
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138683/
https://ncbi.nlm.nih.gov/pubmed/32601441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0452-2
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