Dimethyl itaconate protects against lipopolysaccharide-induced endometritis by inhibition of TLR4/NF-κB and activation of Nrf2/HO-1 signaling pathway in mice

OBJECTIVE(S): Endometritis is the inflammation of the uterine lining that is associated with infertility. It affects milk production and reproductive performance and leads to huge economic losses in dairy cows. Dimethyl itaconate (DI), a promising chemical agent, has recently been proved to have mul...

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Publicado en:Iran J Basic Med Sci
Main Authors: Xu, Mingyue, Jiang, Peng, Sun, Haowen, Yuan, Xin, Gao, Siyuan, Guo, Jian, Zhao, Caijun, Hu, Xiaoyu, Liu, Xueshibojie, Fu, Yunhe
Formato: Artigo
Idioma:Inglês
Publicado: Mashhad University of Medical Sciences 2020
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491490/
https://ncbi.nlm.nih.gov/pubmed/32963747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44151.10346
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