Dimethyl itaconate protects against lipopolysaccharide-induced endometritis by inhibition of TLR4/NF-κB and activation of Nrf2/HO-1 signaling pathway in mice

OBJECTIVE(S): Endometritis is the inflammation of the uterine lining that is associated with infertility. It affects milk production and reproductive performance and leads to huge economic losses in dairy cows. Dimethyl itaconate (DI), a promising chemical agent, has recently been proved to have mul...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Principais autores: Xu, Mingyue, Jiang, Peng, Sun, Haowen, Yuan, Xin, Gao, Siyuan, Guo, Jian, Zhao, Caijun, Hu, Xiaoyu, Liu, Xueshibojie, Fu, Yunhe
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491490/
https://ncbi.nlm.nih.gov/pubmed/32963747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44151.10346
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