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Nuclease-mediated depletion biases in ribosome footprint profiling libraries

Ribosome footprint profiling is a high-throughput sequencing–based technique that provides detailed and global views of translation in living cells. An essential part of this technology is removal of unwanted, normally very abundant, ribosomal RNA sequences that dominate libraries and increase seque...

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Publicat a:RNA
Autors principals: Zinshteyn, Boris, Wangen, Jamie R., Hua, Boyang, Green, Rachel
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491325/
https://ncbi.nlm.nih.gov/pubmed/32503920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.075523.120
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