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High-resolution ribosome profiling defines discrete ribosome elongation states and translational regulation during cellular stress

Ribosomes undergo substantial conformational changes during translation elongation to accommodate incoming aminoacyl-tRNAs and translocate along the mRNA template. We used multiple elongation inhibitors and chemical probing to define ribosome conformational states corresponding to different sized ri...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Wu, Colin Chih-Chien, Zinshteyn, Boris, Wehner, Karen A., Green, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411040/
https://ncbi.nlm.nih.gov/pubmed/30686592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.12.009
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