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High-resolution ribosome profiling defines discrete ribosome elongation states and translational regulation during cellular stress
Ribosomes undergo substantial conformational changes during translation elongation to accommodate incoming aminoacyl-tRNAs and translocate along the mRNA template. We used multiple elongation inhibitors and chemical probing to define ribosome conformational states corresponding to different sized ri...
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| Udgivet i: | Mol Cell |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411040/ https://ncbi.nlm.nih.gov/pubmed/30686592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.12.009 |
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