Identification of dual positive CD19+/CD3+ T cells in a leukapheresis product undergoing CAR transduction: a case report

BACKGROUND: Chimeric antigen receptor (CAR) therapy and hematopoietic stem cell transplantation (HSCT) are therapeutics for relapsed acute lymphocytic leukemia (ALL) that are increasingly being used in tandem. We identified a non-physiologic CD19+/CD3+ T-cell population in the leukapheresis product...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Schultz, Liora, Patel, Shabnum, Davis, Kara Lynn, Ramakrishna, Sneha, Sahaf, Bita, Bhatia, Neehar, Baggott, Christina, Erickson, Courtney, Majzner, Robbie G, Oak, Jean, Bertaina, Alice, Mackall, Crystal, Feldman, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490929/
https://ncbi.nlm.nih.gov/pubmed/32929049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001073
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