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Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data

Cellular functions are performed by a vast and diverse set of proteoforms. Proteoforms are the specific forms of proteins produced as a result of genetic variations, RNA splicing, and post-translational modifications (PTMs). Top-down mass spectrometric analysis of intact proteins enables proteoform...

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Bibliografski detalji
Izdano u:J Proteome Res
Glavni autori: Schaffer, Leah V., Millikin, Robert J., Shortreed, Michael R., Scalf, Mark, Smith, Lloyd M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490796/
https://ncbi.nlm.nih.gov/pubmed/32584579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00332
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