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Constructing Human Proteoform Families Using Intact-Mass and Top-Down Proteomics with a Multi-Protease Global Post-Translational Modification Discovery Database

Complex human biomolecular processes are made possible by the diversity of human proteoforms. Constructing proteoform families, groups of proteoforms derived from the same gene, is one way to represent this diversity. Comprehensive, high-confidence identification of human proteoforms remains a centr...

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Podrobná bibliografie
Vydáno v:J Proteome Res
Hlavní autoři: Dai, Yunxiang, Buxton, Katherine E., Schaffer, Leah V., Miller, Rachel M., Millikin, Robert J., Scalf, Mark, Frey, Brian L., Shortreed, Michael R., Smith, Lloyd M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890418/
https://ncbi.nlm.nih.gov/pubmed/31479276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00339
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