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Constructing Human Proteoform Families Using Intact-Mass and Top-Down Proteomics with a Multi-Protease Global Post-Translational Modification Discovery Database

Complex human biomolecular processes are made possible by the diversity of human proteoforms. Constructing proteoform families, groups of proteoforms derived from the same gene, is one way to represent this diversity. Comprehensive, high-confidence identification of human proteoforms remains a centr...

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Библиографические подробности
Опубликовано в: :J Proteome Res
Главные авторы: Dai, Yunxiang, Buxton, Katherine E., Schaffer, Leah V., Miller, Rachel M., Millikin, Robert J., Scalf, Mark, Frey, Brian L., Shortreed, Michael R., Smith, Lloyd M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890418/
https://ncbi.nlm.nih.gov/pubmed/31479276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00339
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