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Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

Cell size is fundamental to cell physiology. For example, cell size determines the spatial scale of organelles and intracellular transport and thereby affects biosynthesis. Although some genes that affect mammalian cell size have been identified, the molecular mechanisms through which cell growth dr...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Zatulovskiy, Evgeny, Zhang, Shuyuan, Berenson, Daniel F., Topacio, Benjamin R., Skotheim, Jan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489475/
https://ncbi.nlm.nih.gov/pubmed/32703881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6213
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