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Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

Cell size is fundamental to cell physiology. For example, cell size determines the spatial scale of organelles and intracellular transport and thereby affects biosynthesis. Although some genes that affect mammalian cell size have been identified, the molecular mechanisms through which cell growth dr...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Zatulovskiy, Evgeny, Zhang, Shuyuan, Berenson, Daniel F., Topacio, Benjamin R., Skotheim, Jan M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489475/
https://ncbi.nlm.nih.gov/pubmed/32703881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6213
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