Identification of Novel Rho-Kinase-II Inhibitors with Vasodilatory Activity

[Image: see text] Small GTPase protein Rho-kinase (ROCK) plays an important role in the pathogenesis of hypertension. Inhibition of ROCK II brings about the biochemical changes leading to vascular smooth muscles relaxation, finally resulting into potent antihypertensive activity. In the quest for po...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Med Chem Lett
मुख्य लेखकों: Kesar, Seema, Paliwal, Sarvesh, Mishra, Pooja, Madan, Kirtika, Chauhan, Monika, Chauhan, Neha, Verma, Kanika, Sharma, Swapnil
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2020
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488285/
https://ncbi.nlm.nih.gov/pubmed/32944136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00126
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