Llwytho...

Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular condition. Despite being strongly associated with genetic alterations, wide variation of disease penetrance, expressivity and hallmarks of progression complicate treatment. We aimed to characterize different huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Cell Cardiol
Prif Awduron: Bhagwan, Jamie R., Mosqueira, Diogo, Chairez-Cantu, Karolina, Mannhardt, Ingra, Bodbin, Sara E., Bakar, Mine, Smith, James G.W., Denning, Chris
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Academic Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487780/
https://ncbi.nlm.nih.gov/pubmed/32531470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.06.003
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