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Design, synthesis and biological evaluation of novel benzodioxole derivatives as COX inhibitors and cytotoxic agents

Non-steroidal anti-inflammatory drugs are among the most used drugs. They are competitive inhibitors of cyclooxygenase (COX). Twelve novel compounds (aryl acetate and aryl acetic acid groups) were synthesized in this work in order to identify which one was the most potent and which group was most se...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Chem
Κύριοι συγγραφείς: Hawash, Mohammed, Jaradat, Nidal, Hameedi, Saba, Mousa, Ahmed
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Springer International Publishing 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487730/
https://ncbi.nlm.nih.gov/pubmed/32944715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00706-1
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