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Design, synthesis and biological evaluation of novel benzodioxole derivatives as COX inhibitors and cytotoxic agents

Non-steroidal anti-inflammatory drugs are among the most used drugs. They are competitive inhibitors of cyclooxygenase (COX). Twelve novel compounds (aryl acetate and aryl acetic acid groups) were synthesized in this work in order to identify which one was the most potent and which group was most se...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Hawash, Mohammed, Jaradat, Nidal, Hameedi, Saba, Mousa, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487730/
https://ncbi.nlm.nih.gov/pubmed/32944715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00706-1
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