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Design, synthesis and biological evaluation of novel benzodioxole derivatives as COX inhibitors and cytotoxic agents

Non-steroidal anti-inflammatory drugs are among the most used drugs. They are competitive inhibitors of cyclooxygenase (COX). Twelve novel compounds (aryl acetate and aryl acetic acid groups) were synthesized in this work in order to identify which one was the most potent and which group was most se...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Chem
Päätekijät: Hawash, Mohammed, Jaradat, Nidal, Hameedi, Saba, Mousa, Ahmed
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487730/
https://ncbi.nlm.nih.gov/pubmed/32944715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00706-1
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