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Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed anti-inflammatory and pain relief medications. However, their use is associated with many drawbacks, including mainly serious gastric and renal complications. In an attempt to circumvent these risks, a set of N-(4-bromop...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Gouda, Ahmed M., Ali, Hamed I., Almalki, Waleed H., Azim, Mohamed A., Abourehab, Mohammed A. S., Abdelazeem, Ahmed H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273963/
https://ncbi.nlm.nih.gov/pubmed/26867188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020201
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