Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor

Cholesterol-PIE12-trimer (CPT31) is a potent d-peptide HIV entry inhibitor that targets the highly conserved gp41 N-peptide pocket region. CPT31 exhibited strong inhibitory breadth against diverse panels of primary virus isolates. In a simian-HIV chimeric virus AD8 (SHIVAD8) macaque model, CPT31 pre...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nishimura, Yoshiaki, Francis, J. Nicholas, Donau, Olivia K., Jesteadt, Eric, Sadjadpour, Reza, Smith, Amanda R., Seaman, Michael S., Welch, Brett D., Martin, Malcolm A., Kay, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486783/
https://ncbi.nlm.nih.gov/pubmed/32820072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009700117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars