Hyperpolarized [1-(13)C]pyruvate-to-[1-(13)C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane

Hyperpolarized [1-(13)C]pyruvate magnetic resonance spectroscopic imaging (MRSI) is a noninvasive metabolic-imaging modality that probes carbon flux in tissues and infers the state of metabolic reprograming in tumors. Prevailing models attribute elevated hyperpolarized [1-(13)C]pyruvate-to-[1-(13)C]...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Rao, Yi, Gammon, Seth, Zacharias, Niki M., Liu, Tracy, Salzillo, Travis, Xi, Yuanxin, Wang, Jing, Bhattacharya, Pratip, Piwnica-Worms, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2020
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486767/
https://ncbi.nlm.nih.gov/pubmed/32839325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003537117
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