IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome

Cytokine release syndrome (CRS) is a life-threatening complication induced by systemic inflammatory responses to infections, including bacteria and chimeric antigen receptor T cell therapy. There are currently no immunotherapies with proven clinical efficacy and understanding of the molecular mechan...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kang, Sujin, Tanaka, Toshio, Inoue, Hitomi, Ono, Chikako, Hashimoto, Shoji, Kioi, Yoshiyuki, Matsumoto, Hisatake, Matsuura, Hiroshi, Matsubara, Tsunehiro, Shimizu, Kentaro, Ogura, Hiroshi, Matsuura, Yoshiharu, Kishimoto, Tadamitsu
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486751/
https://ncbi.nlm.nih.gov/pubmed/32826331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010229117
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky