Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation

Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD). However, undesirable water solubility of RES reduces its oral bioavailability and demonstrates low efficacy in blood and brain, thus limit...

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Опубликовано в: :Asian J Pharm Sci
Главные авторы: Xiong, Sha, Liu, Wei, Zhou, Yile, Mo, Yousheng, Liu, Yao, Chen, Xiaojia, Pan, Huafeng, Yuan, Dongsheng, Wang, Qi, Chen, Tongkai
Формат: Artigo
Язык:Inglês
Опубликовано: Shenyang Pharmaceutical University 2020
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Original Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486547/
https://ncbi.nlm.nih.gov/pubmed/32952674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.04.003
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