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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation

Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD). However, undesirable water solubility of RES reduces its oral bioavailability and demonstrates low efficacy in blood and brain, thus limit...

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Vydáno v:Asian J Pharm Sci
Hlavní autoři: Xiong, Sha, Liu, Wei, Zhou, Yile, Mo, Yousheng, Liu, Yao, Chen, Xiaojia, Pan, Huafeng, Yuan, Dongsheng, Wang, Qi, Chen, Tongkai
Médium: Artigo
Jazyk:Inglês
Vydáno: Shenyang Pharmaceutical University 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486547/
https://ncbi.nlm.nih.gov/pubmed/32952674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.04.003
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