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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation

Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD). However, undesirable water solubility of RES reduces its oral bioavailability and demonstrates low efficacy in blood and brain, thus limit...

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Detalhes bibliográficos
Main Authors: Sha Xiong, Wei Liu, Yile Zhou, Yousheng Mo, Yao Liu, Xiaojia Chen, Huafeng Pan, Dongsheng Yuan, Qi Wang, Tongkai Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-07-01
Colecção:Asian Journal of Pharmaceutical Sciences
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1818087618313230
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