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How We Think about Targeting RNA with Small Molecules

RNA offers nearly unlimited potential as a target for small molecule chemical probes and lead medicines. Many RNAs fold into structures that can be selectively targeted with small molecules. This Perspective discusses molecular recognition of RNA by small molecules and highlights key enabling techno...

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Pubblicato in:J Med Chem
Autori principali: Costales, Matthew G., Childs-Disney, Jessica L., Haniff, Hafeez S., Disney, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486258/
https://ncbi.nlm.nih.gov/pubmed/32212706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b01927
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