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Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation
Synchrotron radiolysis generates hydroxyl radicals (•OH) that are successful footprinting reagents. Here, we describe a new reagent for the synchrotron platform, the trifluoromethyl radical (•CF(3)). The radical is produced by •OH displacement of •CF(3) from sodium triflinate (Langlois reagent). Upo...
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| Published in: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7486011/ https://ncbi.nlm.nih.gov/pubmed/32255631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00085 |
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