Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study

Determining factors that contribute to interindividual and intra‐individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans. Intestinal microbes are important contributors to variability; however, such gut microbe‐drug interactions and th...

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Bibliografiske detaljer
Udgivet i:Clin Transl Sci
Main Authors: Jarmusch, Alan K., Vrbanac, Alison, Momper, Jeremiah D., Ma, Joseph D., Alhaja, Maher, Liyanage, Marlon, Knight, Rob, Dorrestein, Pieter C., Tsunoda, Shirley M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485946/
https://ncbi.nlm.nih.gov/pubmed/32216086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12785
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