Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study

Determining factors that contribute to interindividual and intra‐individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans. Intestinal microbes are important contributors to variability; however, such gut microbe‐drug interactions and th...

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Detaylı Bibliyografya
Yayımlandı:Clin Transl Sci
Asıl Yazarlar: Jarmusch, Alan K., Vrbanac, Alison, Momper, Jeremiah D., Ma, Joseph D., Alhaja, Maher, Liyanage, Marlon, Knight, Rob, Dorrestein, Pieter C., Tsunoda, Shirley M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485946/
https://ncbi.nlm.nih.gov/pubmed/32216086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12785
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