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Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators

Since the discovery of the GABA(B) agonist and muscle relaxant, baclofen, there have been substantial advancements in the development of compounds that activate the GABA(B) receptor as agonists or positive allosteric modulators. For the agonists, most of the existing structure–activity data applies...

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Bibliografski detalji
Izdano u:J Med Chem
Glavni autori: Brown, Katie M., Roy, Kuldeep K., Hockerman, Gregory H., Doerksen, Robert J., Colby, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485174/
https://ncbi.nlm.nih.gov/pubmed/25856547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5018913
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