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Photoproximity Profiling of Protein-Protein Interactions in Cells

We report a novel photoproximity protein interaction (PhotoPPI) profiling method to map protein-protein interactions in vitro and in live cells. This approach utilizes a bioorthogonal, multifunctional chemical probe that can be targeted to a genetically encoded protein of interest (POI) through a mo...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Autores principales: McCutcheon, David C., Lee, Gihoon, Carlos, Anthony, Montgomery, Jeffrey E., Moellering, Raymond E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484951/
https://ncbi.nlm.nih.gov/pubmed/31820968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b06528
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