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PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation

The discovery of a highly selective putative sigma-1 (σ1) receptor agonist, PRE-084, has revealed the numerous potential uses of this receptor subtype as a therapeutic target. While much work has been devoted to determining the role of σ1 receptors in normal and pathophysiological states in the nerv...

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Détails bibliographiques
Publié dans:Int J Biochem Cell Biol
Auteurs principaux: Motawe, Zeinab Y., Abdelmaboud, Salma S., Cuevas, Javier, Breslin, Jerome W.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484451/
https://ncbi.nlm.nih.gov/pubmed/32668330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2020.105803
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