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Sigma-1 Receptor Activation-Induced Glycolytic ATP Production and Endothelial Barrier Enhancement

OBJECTIVE: We tested the hypothesis that sigma receptor-1 (σ1) modulates endothelial barrier function due to its influence on endothelial bioenergetics. METHODS: Cultured human umbilical vein endothelial cell (HUVEC) monolayers were used to model the endothelial barrier. Electric cell-substrate impe...

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Detalhes bibliográficos
Publicado no:Microcirculation
Main Authors: Motawe, Zeinab Y., Farsaei, Forouzandeh, Abdelmaboud, Salma S., Cuevas, Javier, Breslin, Jerome W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821090/
https://ncbi.nlm.nih.gov/pubmed/32279379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12620
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