Protective effects of the sigma agonist Pre‐084 in the rat retina

AIM: With the rationale that amyloid beta (AB) is toxic to the retina, we here assessed the role of TRAIL, a mediator of AB toxicity and related signal transduction, in a rat model. We also attempted to demonstrate possible protective effects of σ1 receptor agonists in these processes. METHODS: AB a...

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Bibliografski detalji
Glavni autori: Cantarella, Giuseppina, Bucolo, Claudio, Benedetto, Giulia Di, Pezzino, Salvatore, Lempereur, Laurence, Calvagna, Rosa, Clementi, Silvia, Pavone, Piero, Fiore, Lucia, Bernardini, Renato
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2007
Teme:
Scientific Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001020/
https://ncbi.nlm.nih.gov/pubmed/17522150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2007.118570
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