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SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-β/BMP pathway

The SRF/MRTF and upstream signaling cascade play key roles in actin cytoskeleton organization and myocyte development. To date, how this signaling axis may function in brown adipocyte lineage commitment and maturation has not been delineated. Here we report that MRTF-SRF signaling exerts inhibitory...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Liu, Ruya, Xiong, Xuekai, Nam, Deokhwa, Yechoor, Vijay, Ma, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484394/
https://ncbi.nlm.nih.gov/pubmed/32603734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.110920
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