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SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-β/BMP pathway
The SRF/MRTF and upstream signaling cascade play key roles in actin cytoskeleton organization and myocyte development. To date, how this signaling axis may function in brown adipocyte lineage commitment and maturation has not been delineated. Here we report that MRTF-SRF signaling exerts inhibitory...
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| Udgivet i: | Mol Cell Endocrinol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484394/ https://ncbi.nlm.nih.gov/pubmed/32603734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.110920 |
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