The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathways

The molecular clock is intimately linked to metabolic regulation, and brown adipose tissue plays a key role in energy homeostasis. However, whether the cell-intrinsic clock machinery participates in brown adipocyte development is unknown. Here, we show that Bmal1 (also known as ARNTL), the essential...

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Vydáno v:J Cell Sci
Hlavní autoři: Nam, Deokhwa, Guo, Bingyan, Chatterjee, Somik, Chen, Miao-Hsueh, Nelson, David, Yechoor, Vijay K., Ma, Ke
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446734/
https://ncbi.nlm.nih.gov/pubmed/25749863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167643
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