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Diversity Outbred Mice Reveal The Quantitative Trait Locus and Regulatory Cells of HER2 Immunity

The genetic basis and mechanisms of disparate anti-tumor immune response was investigated in Diversity Outbred (DO) F1 mice that express human HER2. DO mouse stock samples nearly the entire genetic repertoire of the species. We crossed DO mice with syngeneic HER2 transgenic mice to study the genetic...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Wei, Wei-Zen, Gibson, Heather M., Jacob, Jennifer B., Frelinger, Jeffrey A., Berzofsky, Jay A., Maeng, Hoyoung, Dyson, Gregory, Reyes, Joyce D., Pilon-Thomas, Shari, Ratner, Stuart, Wei, Kuang-Chung
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484363/
https://ncbi.nlm.nih.gov/pubmed/32796024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000466
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