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Diversity Outbred Mice Reveal The Quantitative Trait Locus and Regulatory Cells of HER2 Immunity

The genetic basis and mechanisms of disparate anti-tumor immune response was investigated in Diversity Outbred (DO) F1 mice that express human HER2. DO mouse stock samples nearly the entire genetic repertoire of the species. We crossed DO mice with syngeneic HER2 transgenic mice to study the genetic...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Wei, Wei-Zen, Gibson, Heather M., Jacob, Jennifer B., Frelinger, Jeffrey A., Berzofsky, Jay A., Maeng, Hoyoung, Dyson, Gregory, Reyes, Joyce D., Pilon-Thomas, Shari, Ratner, Stuart, Wei, Kuang-Chung
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484363/
https://ncbi.nlm.nih.gov/pubmed/32796024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000466
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