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The intrinsic apoptotic pathway lies upstream of oxidative stress in multiple organs
Oxidative stress increases with age in multiple organ systems and is implicated in the development of age-related pathologies in them. Studies from our laboratory show that the intrinsic pathway proapoptotic proteins BAX and caspase-3 (CASP3) lie upstream of mitochondrial production of oxidative str...
Shranjeno v:
| izdano v: | Free Radic Biol Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484315/ https://ncbi.nlm.nih.gov/pubmed/32659346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.05.025 |
| Oznake: |
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