Single Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm

OBJECTIVE: To delineate temporal and spatial dynamics of vascular smooth muscle (SMC) transcriptomic changes during aortic aneurysm development in Marfan syndrome (MFS). APPROACH AND RESULTS: We performed single-cell RNA sequencing (scRNAseq) to study aortic root/ascending aneurysm tissue from Fbn1(...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Pedroza, Albert J., Tashima, Yasushi, Shad, Rohan, Cheng, Paul, Wirka, Robert, Churovich, Samantha, Nakamura, Ken, Yokoyama, Nobu, Cui, Jason Z., Iosef, Cristiana, Hiesinger, William, Quertermous, Thomas, Fischbein, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484233/
https://ncbi.nlm.nih.gov/pubmed/32698686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314670
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker