Divergent effects of canonical and non‐canonical TGF‐β signalling on mixed contractile‐synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms

Aortic root aneurysm formation is a cardinal feature of Marfan syndrome (MFS) and likely TGF‐β driven via Smad (canonical) and ERK (non‐canonical) signalling. The current study assesses human MFS vascular smooth muscle cell (SMC) phenotype, focusing on individual contributions by Smad and ERK, with...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Pedroza, Albert J., Koyano, Tiffany, Trojan, Jeffrey, Rubin, Adam, Palmon, Itai, Jaatinen, Kevin, Burdon, Grayson, Chang, Paul, Tashima, Yasushi, Cui, Jason Z., Berry, Gerry, Iosef, Cristiana, Fischbein, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011150/
https://ncbi.nlm.nih.gov/pubmed/31886938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14921
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars