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The Lon protease links nucleotide metabolism with proteotoxic stress
During proteotoxic stress bacteria maintain critical processes like DNA replication while removing misfolded proteins, which are degraded by the Lon protease. Here, we show that in Caulobacter crescentus Lon controls dNTP pools during stress through degradation of the transcription factor CcrM. Elev...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484108/ https://ncbi.nlm.nih.gov/pubmed/32755596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.07.011 |
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