Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation

Clostridioides difficile toxin A (TcdA) has been shown to inhibit cellular Wnt signaling, the major driving force behind the proliferation of epithelial cells in colonic crypts, likely through the inhibition of β-catenin nuclear translocation. Herein, we aimed to advance the understanding of this me...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Microbiol
Päätekijät: Martins, Conceição S., Costa, Deiziane V. S., Lima, Bruno B., Leitäo, Renata F. C., Freire, Gildênio E., Silva, Guilherme F. M., Pacífico, Dvison M., Abreu, José G., Brito, Gerly A. C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Microbiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483921/
https://ncbi.nlm.nih.gov/pubmed/32983019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01998
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia