Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation

Clostridioides difficile toxin A (TcdA) has been shown to inhibit cellular Wnt signaling, the major driving force behind the proliferation of epithelial cells in colonic crypts, likely through the inhibition of β-catenin nuclear translocation. Herein, we aimed to advance the understanding of this me...

詳細記述

保存先:
書誌詳細
出版年:Front Microbiol
主要な著者: Martins, Conceição S., Costa, Deiziane V. S., Lima, Bruno B., Leitäo, Renata F. C., Freire, Gildênio E., Silva, Guilherme F. M., Pacífico, Dvison M., Abreu, José G., Brito, Gerly A. C.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
Microbiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483921/
https://ncbi.nlm.nih.gov/pubmed/32983019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01998
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