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Inhibition of TREM-1 with an eCIRP-derived Peptide Protects Mice from Intestinal Ischemia-reperfusion Injury

INTRODUCTION: Intestinal ischemia-reperfusion (I-I/R) injury results in morbidity and mortality from both local injury and systemic inflammation and acute lung injury (ALI). Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage associated molecular pattern (DAMP) that fuels systemic i...

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發表在:Surgery
Main Authors: Denning, Naomi-Liza, Aziz, Monowar, Ochani, Mahendar, Prince, Jose M., Wang, Ping
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483826/
https://ncbi.nlm.nih.gov/pubmed/32439208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2020.04.010
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