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Advances in G Protein-Coupled Receptor High-throughput Screening

G protein-coupled receptors (GPCRs) detect compounds on the cell surface and are the starting point of a number of medically relevant signaling cascades. Indeed, over 30% of FDA approved drugs target GPCRs, making them a primary target for drug discovery. Computational and experimental high-throughp...

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發表在:Curr Opin Biotechnol
Main Authors: Yasi, Emily A., Kruyer, Nicholas S., Peralta-Yahya, Pamela
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483569/
https://ncbi.nlm.nih.gov/pubmed/32653805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2020.06.004
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